SCHEMBL6464880

SCHEMBL6464880

C=CC(=O)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
GAA P10253 3/20 0.37
POLB P06746 2/20 0.33
RECQL P46063 1/20 0.32
APLNR P35414 1/20 0.32
ALDH1A1 P00352 1/20 0.31
EZH2 Q15910 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTT P42858 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16353458 0.78 GAA (0.33) GAAPOLBRECQLAPLNRALDH1A1
Acrylic Acid SCHEMBL9813704 0.78 LMNA (0.40) GAAPOLBRECQLAPLNRALDH1A1
SCHEMBL11497231 0.75 GAA (0.39) GAAPOLBRECQLAPLNRALDH1A1
SCHEMBL9515587 0.73 THRA (0.38) THRATHRBAPLNR
SCHEMBL11455039 0.73 APLNR (0.45) GAAPOLBAPLNRALDH1A1EZH2
SCHEMBL27495162 0.73 GAA (0.38) GAAPOLBRECQLAPLNRALDH1A1
SCHEMBL83010 0.73 APLNR (0.61) GAAPOLBRECQLAPLNRALDH1A1
SCHEMBL12805455 0.72 THRA (0.37) THRATHRBAPLNR
SCHEMBL10809057 0.72 GAA (0.39) GAAALDH1A1
SCHEMBL5087932 0.71 GAA (0.37) GAAPOLBRECQLAPLNRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5910213-A PARTICULATE, PIGMENTARY MATERIAL TREATED WITH A POLYMERIC HINDERED AMINE STABILIZER TIOXIDE GROUP SERVICES LIMITED (GB) 1999-06-08 US claimed
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP claimed
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US claimed
JP-1110670-A None JP disclosed
EP-1155058-B1 STABILIZING AGENT DEGUSSA (DE) 2005-03-16 EP disclosed
US-5910213-A PARTICULATE, PIGMENTARY MATERIAL TREATED WITH A POLYMERIC HINDERED AMINE STABILIZER TIOXIDE GROUP SERVICES LIMITED (GB) 1999-06-08 US disclosed
EP-0824137-A2 Titanium dioxide treated with polymeric hindered amine stabilisers TIOXIDE GROUP SERVICES LIMITED (GB) 1998-02-18 EP disclosed
US-5330669-A Polyurethane with phosphorus acid group KYOWA HAKKO KOGYO CO., LTD. (US) 1994-07-19 US disclosed
US-5292853-A Magnetic recording media KYOWA HAKKO KOGYO CO., LTD. (US) 1994-03-08 US disclosed
US-5273826-A Polyurethane containing phosphorus groups as binder THE B. F. GOODRICH COMPANY (US) 1993-12-28 US disclosed
EP-0307041-B1 Sterically hindered amino compounds and processes for their preparation ENIRICERCHE SPA (IT) 1993-12-15 EP disclosed
EP-0355880-B1 Ethylene copolymers and process for preparing them ENIRICERCHE SPA (IT) 1993-12-08 EP disclosed
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP disclosed
US-4980477-A POLYMER STABILIZERS; PHOTOSTABILITY TO UV RAD ENIRICERCHE SPA (IT) 1990-12-25 US disclosed
EP-0355880-A2 Ethylene copolymers and process for preparing them ENIRICERCHE S.p.A. (IT) 1990-02-28 EP disclosed
JP-H01110670-A STERICALLY HINDERED AMINO COMPOUND ENIRICERCHE SPA 1989-04-27 JP disclosed
EP-0307041-A2 Sterically hindered amino compounds and processes for their preparation ENIRICERCHE S.p.A. (IT) 1989-03-15 EP disclosed