SCHEMBL646556

SCHEMBL646556

O=C(O)c1ccc(F)nc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HA1 P13674 3/20 0.61
P4HTM Q9NXG6 2/20 0.61
MIF P14174 1/20 0.59
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57
GABRG1 Q8N1C3 1/20 0.57
GABRG3 Q99928 1/20 0.57
GABRQ Q9UN88 1/20 0.57
NAPRT Q6XQN6 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29723813 1.00 P4HA1 (0.61) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL29646483 1.00 P4HA1 (0.61) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL30448953 1.00 P4HA1 (0.61) P4HA1P4HTMMIFGABRPGABRD
Hydrochloric Acid SCHEMBL698501 0.98 P4HA1 (0.59) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL27594193 0.84 RXFP1 (0.53) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL2042090 0.84 BCL2L1 (0.59) HSD17B10TP53TSHRBCL2L1BAD
SCHEMBL29788190 0.84 BCL2L1 (0.59) HSD17B10TP53TSHRBCL2L1BAD
SCHEMBL691934 0.80 NAPRT (0.45) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL18910409 0.80 KCNQ3 (0.44) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL2514243 0.80 KCNQ3 (0.44) P4HA1P4HTMMIFGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823035-A Preparation method of m-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2025-04-15 CN claimed
CN-119823033-A Synthesis method of 2-fluoropyridine-5-formyl chloride 湖南化工研究院有限公司 2025-04-15 CN claimed
WO-2024245356-A1 M-AMIDOBENZOIC ACID BISAMIDE COMPOUND AND INTERMEDIATE THEREOF 湖南化工研究院有限公司 2024-12-05 WO claimed
EP-4008718-B1 HETEROARYLAMIDOPYRIDINOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE INNOVO THERAPEUTICS INC (KR) 2024-10-30 EP claimed
CN-115433122-B Preparation method of 6-fluoro nicotinic acid 大连双硼医药化工有限公司 2024-01-30 CN claimed
CN-116987064-B Preparation method and application of pyrimidine bisnicotinamide derivative 宁夏佰斯特医药化工有限公司 2024-01-26 CN claimed
CN-116987064-A Preparation method and application of pyrimidine bisnicotinamide derivative 宁夏佰斯特医药化工有限公司 2023-11-03 CN claimed
CN-115869923-A Oxygen absorbing material, preparation method thereof and prepared adsorbing material capable of adsorbing oxygen and organic solvent simultaneously 威格科技(苏州)股份有限公司 2023-03-31 CN claimed
CN-113912592-B Honokiol dihydrofuran ester derivative, preparation method and application thereof 西北农林科技大学 2023-03-10 CN claimed
CN-115433122-A Preparation method of 6-fluoronicotinic acid 大连双硼医药化工有限公司 2022-12-06 CN claimed
CN-115260176-A Pyrazole amide derivative containing oxazole group and preparation method and application thereof 安徽农业大学 2022-11-01 CN claimed
CN-113046734-A Bivalent palladium complex solution and preparation method and application thereof 上海天承化学有限公司 2021-06-29 CN claimed
CN-120590466-B Compound of targeted fibroblast activation protein and application thereof 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) 2026-05-12 CN disclosed
CN-121824416-A Method for preparing 6-fluoronicotinic acid based on heterogeneous catalytic system 苏州艾缇克药物化学有限公司 2026-04-10 CN disclosed
CN-121824416-A Method for preparing 6-fluoronicotinic acid based on heterogeneous catalytic system 苏州艾缇克药物化学有限公司 2026-04-10 CN disclosed
US-20260091148-A1 DIAGNOSTIC PET IMAGING OF CARDIAC AMYLOIDOSIS Higuchi, Takahiro (DE) 2026-04-02 US disclosed
US-4358455-A GLAUCOMA, HYPOTENSIVE, ANTIARRHYTHMIA, BRONCHODILATORS MERCK & CO., INC. (US) 1982-11-09 US disclosed
US-4046768-A 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed
US-4045446-A 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-30 US disclosed
US-4033753-A HERICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091148-A1 DIAGNOSTIC PET IMAGING OF CARDIAC AMYLOIDOSIS TNNC1, TNNT2, TNNI3 P4HA1 1565/4885P4HTM 3740/4885MIF 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.