Sugi Predict

Sugi Predict / Compounds / SCHEMBL691934

SCHEMBL691934

SCHEMBL691934

O=C(Cl)c1ccc(F)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NAPRT Q6XQN6 1/20 0.45
▸ KCNQ3 O43525 3/20 0.44
▸ KCNQ2 O43526 3/20 0.44
▸ EPHX2 P34913 1/20 0.43
▸ P4HA1 P13674 2/20 0.39
▸ P4HTM Q9NXG6 2/20 0.39
▸ KCNE1 P15382 2/20 0.39
▸ KCNQ1 P51787 2/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ MIF P14174 1/20 0.38
▸ KDM1A O60341 1/20 0.37
▸ RCOR1 Q9UKL0 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ SLC18A3 Q16572 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.36
▸ GABRP O00591 1/20 0.36
▸ GABRD O14764 1/20 0.36
▸ GABRA1 P14867 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27594193 0.82 RXFP1 (0.53) NAPRTKCNQ3KCNQ2EPHX2P4HA1
SCHEMBL646556 0.80 P4HA1 (0.61) NAPRTEPHX2P4HA1P4HTMMIF
SCHEMBL29646483 0.80 P4HA1 (0.61) NAPRTEPHX2P4HA1P4HTMMIF
SCHEMBL30448953 0.80 P4HA1 (0.61) NAPRTEPHX2P4HA1P4HTMMIF
SCHEMBL29723813 0.80 P4HA1 (0.61) NAPRTEPHX2P4HA1P4HTMMIF
SCHEMBL18910409 0.78 KCNQ3 (0.44) NAPRTKCNQ3KCNQ2EPHX2P4HA1
SCHEMBL15274452 0.78 KCNJ1 (0.46) KCNQ3KCNQ2EPHX2P4HA1P4HTM
Hydrochloric Acid SCHEMBL698501 0.78 P4HA1 (0.59) NAPRTKCNQ3KCNQ2EPHX2P4HA1
SCHEMBL30074590 0.78 NNMT (0.61) KCNQ3KCNQ2EPHX2NNMTSMN1; SMN2
SCHEMBL2514243 0.78 KCNQ3 (0.44) NAPRTKCNQ3KCNQ2EPHX2P4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823035-A Preparation method of m-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2025-04-15 — — CN claimed
CN-119684286-A Synthesis method of key intermediate of celecoxib 苏州莱安医药化学技术有限公司 2025-03-25 — — CN claimed
US-12551490-B2 Heterocyclic modulators of lipid synthesis SAGIMET BIOSCIENCES INC. (US) 2026-02-17 — — US disclosed
US-20250353850-A1 CYCLIC AMIDE-CONTAINING PYRIDYL XANTHINES AS A2B ANTAGONISTS ADOVATE LLC (US) 2025-11-20 — — US disclosed
US-12358910-B2 Heteroaromatic compounds as Vanin inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-07-15 — — US disclosed
CN-119823035-A Preparation method of m-aminobenzoic acid bisamide compound 湖南化工研究院有限公司 2025-04-15 — — CN disclosed
CN-119823033-A Synthesis method of 2-fluoropyridine-5-formyl chloride 湖南化工研究院有限公司 2025-04-15 — — CN disclosed
CN-113166117-B Heteroaromatic compounds as VANIN inhibitors 勃林格殷格翰国际公司 2025-04-15 — — CN disclosed
US-12269828-B2 Cyclic amide-containing pyridyl xanthines as A2B antagonists ADOVATE, LLC (US) 2025-04-08 — — US disclosed
CN-115611767-B Amide compound and application thereof 沈阳化工大学 2025-03-25 — — CN disclosed
CN-119684286-A Synthesis method of key intermediate of celecoxib 苏州莱安医药化学技术有限公司 2025-03-25 — — CN disclosed
US-5583148-A FUNGICIDE, BACTERICIDE AND ANTICARCINOGENIC AGENT RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-12-10 — — US disclosed
CN-1133045-A 7-azabicyclo-[2,2,1]-heptane and-heptene derivatives as analgesics and anti-inflammatory agents UNIV VIRGINIA (US) 1996-10-09 — — CN disclosed
WO-1996006093-A1 7-AZABICYCLO[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS UNIVERSITY OF VIRGINIA (US) 1996-02-29 — — WO disclosed
EP-0691971-A1 7-AZABICYCLO- 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS UNIVERSITY OF VIRGINIA (US) 1996-01-17 — — EP disclosed
WO-1994022868-A1 7-AZABICYCLO-[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS UNIVERSITY OF VIRGINIA (US) 1994-10-13 — — WO disclosed
EP-0479951-A4 BIS-ACYLOXYMETHYL DERIVATIVES — 1992-12-09 — — EP disclosed
EP-0479951-A1 BIS-ACYLOXYMETHYL DERIVATIVES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1992-04-15 — — EP disclosed
EP-0477678-A1 O-Acyl formaldoxime-pyridines, process for their preparation and their use as microbicides NIHON BAYER AGROCHEM K.K. (JP) 1992-04-01 — — EP disclosed
WO-1991000093-A1 BIS-ACYLOXYMETHYL DERIVATIVES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1991-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358910-B2 Heteroaromatic compounds as Vanin inhibitors VHL, FANCI, PAH NAPRT 784/4885KCNQ3 1189/4885KCNQ2 656/4885
US-12551490-B2 Heterocyclic modulators of lipid synthesis FASN, FADS1, FADS2 NAPRT 1030/4885KCNQ3 4265/4885KCNQ2 4321/4885
US-20250353850-A1 CYCLIC AMIDE-CONTAINING PYRIDYL XANTHINES AS A2B ANTAGONISTS ADORA2B, ADORA2A, ADORA1 NAPRT 218/4885KCNQ3 2806/4885KCNQ2 2016/4885
US-12269828-B2 Cyclic amide-containing pyridyl xanthines as A2B antagonists ADORA2B, ADORA2A, ADORA1 NAPRT 218/4885KCNQ3 2806/4885KCNQ2 2016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.