Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068587 | 0.87 | HSD11B1 (0.30) | HSD11B1HSD11B2 | |
| SCHEMBL29033699 | 0.75 | EPHX2 (0.38) | EPHX2EPHX1HSD11B1SIGMAR1 | |
| SCHEMBL5734633 | 0.72 | GRIN2D (0.34) | EPHX2EPHX1HSD11B1SIGMAR1 | |
| SCHEMBL4061204 | 0.70 | SIGMAR1 (0.34) | EPHX2SIGMAR1 | |
| SCHEMBL20724768 | 0.69 | EPHX2 (0.40) | EPHX2HSD11B1HSD11B2 | |
| SCHEMBL19808239 | 0.69 | EPHX2 (0.40) | EPHX2HSD11B1HSD11B2 | |
| SCHEMBL19808243 | 0.69 | EPHX2 (0.40) | EPHX2HSD11B1HSD11B2 | |
| SCHEMBL19808587 | 0.65 | LMNA (0.51) | EPHX2HSD11B1HSD11B2 | |
| SCHEMBL19808662 | 0.65 | NPC1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL6465665 | 0.64 | EPHX2 (0.33) | EPHX2HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534427-A1 | AN ADAMANTYL CATALYTIC SYSTEM | Lucite International UK Limited (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004014552-A1 | A PHOSPHA-ADAMANTANE (S) CATALYTIC SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |