Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078719 | 0.93 | — | — | |
| SCHEMBL14190758 | 0.87 | HSD11B1 (0.30) | HSD11B1HSD11B2 | |
| SCHEMBL289717 | 0.82 | OPRK1 (0.42) | EPHX2HSD11B1OPRK1ALDH1A1TSHR | |
| Bromide SCHEMBL1478373 | 0.80 | OPRK1 (0.41) | EPHX2HSD11B1OPRK1ALDH1A1TSHR | |
| SCHEMBL5738047 | 0.80 | OPRK1 (0.41) | EPHX2HSD11B1OPRK1ALDH1A1TSHR | |
| SCHEMBL2015640 | 0.77 | ALDH1A1 (0.39) | OPRK1ALDH1A1TSHRHPGDP2RX7 | |
| SCHEMBL14755281 | 0.76 | HSD11B1 (0.34) | EPHX2HSD11B1ALDH1A1TSHRHPGD | |
| SCHEMBL21562234 | 0.75 | HSD11B1 (0.37) | EPHX2HSD11B1OPRK1ALDH1A1TSHR | |
| SCHEMBL5734637 | 0.75 | HSD11B1 (0.34) | EPHX2HSD11B1OPRK1ALDH1A1TSHR | |
| SCHEMBL2011475 | 0.73 | HPGD (0.39) | EPHX2HSD11B1OPRK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534427-A1 | AN ADAMANTYL CATALYTIC SYSTEM | Lucite International UK Limited (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004014552-A1 | A PHOSPHA-ADAMANTANE (S) CATALYTIC SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |