Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716415 | 0.81 | LMNA (0.30) | LMNA | |
| SCHEMBL8644493 | 0.75 | LMNA (0.52) | DRD4LMNA | |
| SCHEMBL189494 | 0.74 | LMNA (0.50) | LMNA | |
| SCHEMBL998473 | 0.71 | LMNA (0.42) | LMNA | |
| SCHEMBL8961761 | 0.71 | MAPT (0.31) | LMNA | |
| SCHEMBL433832 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL8457618 | 0.70 | HRH4 (0.40) | — | |
| SCHEMBL1450474 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL2712916 | 0.70 | KEAP1 (0.47) | LMNA | |
| SCHEMBL10757031 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |