SCHEMBL6465694

SCHEMBL6465694

Cc1ccc(S(=O)(=O)NC(=O)Nc2nc[nH]n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
USP2 O75604 1/20 0.54
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PKM P14618 1/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA13 Q8N1Q1 2/20 0.52
CA14 Q9ULX7 2/20 0.52
TP53 P04637 1/20 0.52
KDM4E B2RXH2 1/20 0.52
FBP1 P09467 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463108 0.80 LMNA (0.64) LMNAKMT2AMEN1USP2ALDH1A1
SCHEMBL8553736 0.77 LMNA (0.60) LMNAKMT2AMEN1USP2ALDH1A1
SCHEMBL4069135 0.77 LMNA (0.56) LMNAKMT2AMEN1USP2ALDH1A1
SCHEMBL6465229 0.76 KDM4E (0.63) LMNAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL5184740 0.75 LMNA (0.69) LMNAKMT2AALDH1A1CA12CA1
SCHEMBL1928662 0.75 CA12 (0.85) LMNAKMT2AMEN1USP2ALDH1A1
SCHEMBL6243996 0.75 CA12 (0.85) LMNAKMT2AMEN1USP2ALDH1A1
SCHEMBL2755807 0.74 ALDH1A1 (0.39) KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL19268210 0.74 RAB9A (0.51) KMT2AALDH1A1SMN1; SMN2PKMTP53
SCHEMBL8551342 0.73 LMNA (0.54) LMNAKMT2AMEN1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed