Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700294 | 0.80 | LMNA (0.36) | LMNAKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6465694 | 0.77 | LMNA (0.55) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5184740 | 0.77 | LMNA (0.69) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL6243996 | 0.76 | CA12 (0.85) | LMNAALDH1A1KMT2ATP53CA12 | |
| SCHEMBL1928662 | 0.76 | CA12 (0.85) | LMNAALDH1A1KMT2ATP53CA12 | |
| SCHEMBL6466801 | 0.75 | LMNA (1.00) | LMNAKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6465388 | 0.75 | KDM4E (1.00) | LMNAKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8551342 | 0.74 | LMNA (0.54) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6324634 | 0.73 | CA12 (0.70) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL30020242 | 0.73 | LMNA (0.61) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |