Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469218 | 0.89 | HTT (0.44) | TDP1RECQLALDH1A1LMNAKMT2A | |
| SCHEMBL5563453 | 0.83 | LPAR1 (0.37) | HTTLPAR1LPAR5OPRK1OPRM1 | |
| SCHEMBL6463290 | 0.82 | KMT2A (0.40) | TDP1RECQLALDH1A1LMNAKMT2A | |
| SCHEMBL6468914 | 0.82 | ALDH1A1 (0.43) | TDP1RECQLALDH1A1LMNAHTT | |
| SCHEMBL5559322 | 0.80 | ADRA1D (0.40) | LPAR1LPAR5 | |
| SCHEMBL6463902 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL5563157 | 0.75 | HTT (0.39) | KMT2AMEN1HTTLPAR1LPAR5 | |
| SCHEMBL6468063 | 0.72 | MCHR1 (0.38) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5568028 | 0.70 | HTT (0.40) | KMT2AMEN1HTTLPAR1LPAR5 | |
| SCHEMBL5569023 | 0.70 | HTT (0.42) | HTTLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | disclosed |