Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563099 | 0.80 | ALDH1A1 (0.40) | MCHR1MEN1KMT2AATMHDAC6 | |
| SCHEMBL6463902 | 0.79 | ALDH1A1 (0.54) | LMNAMEN1KMT2AATMALDH1A1 | |
| SCHEMBL6469218 | 0.78 | HTT (0.44) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6466066 | 0.72 | TDP1 (0.41) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5567947 | 0.71 | MCHR1 (0.38) | MCHR1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL6463667 | 0.71 | NPY5R (0.34) | MEN1KMT2AATMMAPT | |
| SCHEMBL6463290 | 0.70 | KMT2A (0.40) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL5567874 | 0.68 | MCHR1 (0.36) | MCHR1LMNAMEN1KMT2AATM | |
| SCHEMBL5568028 | 0.65 | HTT (0.40) | MCHR1MEN1KMT2AATM | |
| SCHEMBL18502047 | 0.64 | HRH3 (0.47) | MCHR1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | claimed |