SCHEMBL6466090

SCHEMBL6466090

Cc1ccc(CS(=O)(=O)NC(=O)Nc2ccc(Cc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
SAE1 Q9UBE0 3/20 0.51
UBA2 Q9UBT2 3/20 0.51
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
TP53 P04637 2/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA7 P43166 1/20 0.49
CA13 Q8N1Q1 1/20 0.49
CA14 Q9ULX7 1/20 0.49
LMNA P02545 1/20 0.48
PTPN7 P35236 1/20 0.48
MET P08581 1/20 0.47
RAB9A P51151 3/20 0.47
PPARG P37231 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463105 0.87 CA1 (0.57) SAE1UBA2CA12CA1CA2
SCHEMBL6469561 0.85 CNR1 (0.50) NPC1SAE1UBA2CA12CA1
SCHEMBL6466493 0.85 SAE1 (0.71) NPC1SAE1UBA2CA12CA1
SCHEMBL6462904 0.83 HPGD (0.58) NPC1SAE1UBA2CA12CA1
SCHEMBL27680 0.82 CA12 (0.72) CA12CA1CA2CA9TP53
SCHEMBL12711073 0.82 SAE1 (0.70) NPC1SAE1UBA2TP53PTPN7
SCHEMBL23486696 0.81 CA12 (0.56) NPC1CA12CA1CA2CA9
SCHEMBL14583063 0.79 NPC1 (0.64) NPC1SAE1UBA2TP53PTPN7
SCHEMBL8626829 0.78 LMNA (0.56) NPC1SAE1UBA2CA12CA1
SCHEMBL13618629 0.78 SAE1 (0.64) NPC1SAE1UBA2TP53PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed