SCHEMBL6466493

SCHEMBL6466493

COc1ccc(CS(=O)(=O)NC(=O)Nc2ccc(Cc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SAE1 Q9UBE0 1/20 0.71
UBA2 Q9UBT2 1/20 0.71
SMN1; SMN2 Q16637 4/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
MET P08581 2/20 0.52
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA9 Q16790 3/20 0.51
HIF1A Q16665 1/20 0.50
HDAC8 Q9BY41 1/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6465689 0.89 RAB9A (0.63) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6466509 0.89 MET (0.61) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6466690 0.87 SAE1 (0.64) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6466090 0.85 NPC1 (0.53) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6467353 0.84 SAE1 (0.71) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6463105 0.83 CA1 (0.57) SAE1UBA2METCA12CA1
SCHEMBL6469561 0.82 CNR1 (0.50) SAE1UBA2NPC1RAB9AKDM4E
SCHEMBL6462904 0.79 HPGD (0.58) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL6464101 0.79 SAE1 (0.55) SAE1UBA2SMN1; SMN2NPC1RAB9A
SCHEMBL15376420 0.78 SMN1; SMN2 (0.53) SMN1; SMN2HDAC8HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed