SCHEMBL6469561

SCHEMBL6469561

O=C(Nc1ccc(Cc2ccc(NC(=O)NS(=O)(=O)Cc3ccc(Cl)cc3)cc2)cc1)NS(=O)(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.50
ALDH1A1 P00352 2/20 0.50
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
SAE1 Q9UBE0 1/20 0.48
UBA2 Q9UBT2 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
NPC1 O15118 2/20 0.47
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RAB9A P51151 2/20 0.47
POLB P06746 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
MET P08581 1/20 0.46
LMNA P02545 2/20 0.46
IDH1 O75874 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091378 0.88 CNR1 (0.57) CNR1ALDH1A1CA12CA1CA2
SCHEMBL6463105 0.87 CA1 (0.57) CA12CA1CA2CA9SAE1
SCHEMBL6466090 0.85 NPC1 (0.53) CNR1CA12CA1CA2CA9
SCHEMBL8417032 0.82 EGFR (0.57) ALDH1A1CA12CA1CA2CA9
SCHEMBL6466493 0.82 SAE1 (0.71) CNR1CA12CA1CA2CA9
SCHEMBL6462904 0.80 HPGD (0.58) ALDH1A1CA12CA1CA2CA9
SCHEMBL6464498 0.76 ACP1 (0.61) CA12CA1CA2CA9MEN1
SCHEMBL8091423 0.76 ALDH1A1 (0.53) CNR1ALDH1A1CA12CA1CA2
SCHEMBL6464378 0.75 SAE1 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL8097633 0.75 ALDH1A1 (0.51) CNR1ALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed