Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214191 | 0.85 | MAPT (0.53) | MAPTGAAPOLBHSD17B10MAPK1 | |
| SCHEMBL29670526 | 0.85 | MAPT (0.62) | MAPTGAAPOLBHSD17B10MAPK1 | |
| SCHEMBL3289240 | 0.85 | MAPT (0.62) | MAPTGAAPOLBHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL11210248 | 0.84 | MAPT (0.52) | MAPTGAAPOLBHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL9847484 | 0.83 | MAPT (0.60) | MAPTGAAPOLBHSD17B10MAPK1 | |
| SCHEMBL5069965 | 0.82 | MAPT (0.69) | MAPTGAAHSD17B10MAPK1KDM4E | |
| SCHEMBL27637318 | 0.81 | MAPT (0.53) | MAPTGAAPOLBHSD17B10MAPK1 | |
| SCHEMBL27585757 | 0.80 | MAPT (0.56) | MAPTGAAPOLBHSD17B10MAPK1 | |
| SCHEMBL22939620 | 0.80 | SPR (0.49) | MAPTGAAHSD17B10KDM4EALOX15 | |
| SCHEMBL9994810 | 0.80 | MAPT (0.56) | MAPTGAAPOLBHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494642-A1 | ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS | DSM IP Assets B.V. (NL) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086340-A1 | ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS | DSM IP ASSETS B.V. (NL) | 2003-10-23 | — | — | WO | disclosed |