Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062216 | 0.86 | SIGMAR1 (0.48) | MEN1KMT2A | |
| SCHEMBL6460781 | 0.85 | CHRM1 (0.39) | PLD1 | |
| SCHEMBL2150109 | 0.74 | MEN1 (0.64) | MEN1KMT2A | |
| SCHEMBL2149712 | 0.72 | CHRM1 (0.63) | — | |
| SCHEMBL2149643 | 0.72 | HTR1A (0.66) | — | |
| SCHEMBL6462861 | 0.69 | POLB (0.50) | MEN1KMT2AMAPK1 | |
| SCHEMBL29591678 | 0.67 | MAPK1 (0.52) | MEN1KMT2AMAPK1 | |
| SCHEMBL2600306 | 0.67 | MAPK1 (0.52) | MEN1KMT2AMAPK1 | |
| SCHEMBL16997531 | 0.66 | TNKS (0.57) | MEN1KMT2APLD1MAPK1 | |
| SCHEMBL6454535 | 0.65 | SIGMAR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432420-A4 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1432420-A2 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | Acadia Pharmaceuticals Inc. (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028650-A2 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |