Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466262 | 0.86 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL2149643 | 0.78 | HTR1A (0.66) | — | |
| SCHEMBL2149712 | 0.78 | CHRM1 (0.63) | — | |
| SCHEMBL2150109 | 0.75 | MEN1 (0.64) | MEN1KMT2A | |
| SCHEMBL6460781 | 0.74 | CHRM1 (0.39) | — | |
| SCHEMBL6454535 | 0.73 | SIGMAR1 (0.44) | SIGMAR1 | |
| SCHEMBL6470338 | 0.69 | POLB (0.47) | MEN1KMT2A | |
| SCHEMBL7069097 | 0.69 | ADRA1D (0.39) | MEN1KMT2A | |
| SCHEMBL7135550 | 0.68 | CHRM1 (0.47) | — | |
| SCHEMBL6451141 | 0.68 | CHRM1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089942-A2 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2004-10-21 | — | — | WO | disclosed |