Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067261 | 0.81 | CHRM1 (0.45) | — | |
| SCHEMBL2150290 | 0.77 | HTR1A (0.66) | — | |
| SCHEMBL2149429 | 0.77 | SIGMAR1 (0.64) | SIGMAR1 | |
| SCHEMBL3028533 | 0.77 | DRD2 (0.60) | — | |
| SCHEMBL7062216 | 0.73 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL7131386 | 0.66 | CHRM1 (0.42) | — | |
| SCHEMBL6466262 | 0.65 | MEN1 (0.49) | — | |
| SCHEMBL5956419 | 0.65 | SLC6A2 (0.52) | — | |
| SCHEMBL2149110 | 0.64 | DRD2 (0.54) | — | |
| SCHEMBL8870136 | 0.64 | HTR1A (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432420-A4 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1432420-A2 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | Acadia Pharmaceuticals Inc. (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028650-A2 | BENZIMIDAZOLIDINONE DERIVATIVES AS MUSCARINIC AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |