Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046899 | 0.88 | CYP3A4 (0.39) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL6468400 | 0.82 | HPGD (0.35) | HPGDALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6475534 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1POLBMAPTKMT2ANPSR1 | |
| SCHEMBL7567547 | 0.72 | ALDH1A1 (0.35) | HPGDALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6467328 | 0.72 | KMT2A (0.35) | HPGDALDH1A1POLBMAPTKMT2A | |
| SCHEMBL7046317 | 0.71 | SLC1A3 (0.39) | MAPTKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL6464575 | 0.70 | LMNA (0.44) | ALDH1A1POLBKMT2ALMNAALOX12 | |
| SCHEMBL6467203 | 0.69 | SMN1; SMN2 (0.35) | HPGDALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6061799 | 0.68 | CYP3A4 (0.38) | ALDH1A1POLBKMT2ALMNAMEN1 | |
| SCHEMBL6467567 | 0.68 | CTSS (0.38) | ALDH1A1POLBMAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |