Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339549 | 0.84 | KCNK3 (0.40) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL1047239 | 0.80 | KCNK3 (0.47) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL5608059 | 0.80 | KCNK3 (0.38) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL29921054 | 0.80 | TRPA1 (0.41) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL23835302 | 0.80 | TRPA1 (0.41) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL28709564 | 0.79 | KCNK3 (0.42) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL807278 | 0.79 | KCNK3 (0.52) | KCNK3KCNK9ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24180095 | 0.78 | KCNK3 (0.38) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4654446 | 0.77 | RXRA (0.47) | KCNK3KCNK9ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL1729802 | 0.76 | KCNK3 (0.43) | KCNK3KCNK9ALDH1A1CYP1A2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | disclosed |
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215821-A1 | N-Substituted Azacycles | DDT, UQCRB, DNMT1 | KCNK3 2739/4885KCNK9 968/4885ALDH1A1 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.