Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466640 | 1.00 | LMNA (0.77) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL8724910 | 0.93 | LMNA (0.67) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL6466162 | 0.90 | LMNA (0.72) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL6463859 | 0.90 | LMNA (0.72) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL6466618 | 0.90 | LMNA (0.72) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL6467789 | 0.90 | LMNA (0.72) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL7588539 | 0.89 | LMNA (0.70) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL5515133 | 0.89 | ALDH1A1 (0.79) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL7078029 | 0.89 | ALDH1A1 (0.79) | LMNACYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL22324528 | 0.89 | LMNA (0.70) | LMNACYP3A4MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951904-B1 | Process for increasing the melt strength of polypropylene | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2005-10-04 | — | — | US | claimed |
| EP-1080148-A4 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LTD (AU) | 2003-02-05 | — | — | EP | claimed |
| EP-1080148-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | Polymers Australia PTY Limited (AU) | 2001-03-07 | — | — | EP | claimed |
| WO-1999036466-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LIMITED (AU) | 1999-07-22 | — | — | WO | claimed |
| US-6951904-B1 | Process for increasing the melt strength of polypropylene | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2005-10-04 | — | — | US | disclosed |
| EP-1080148-A4 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LTD (AU) | 2003-02-05 | — | — | EP | disclosed |
| EP-1080148-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | Polymers Australia PTY Limited (AU) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999036466-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LIMITED (AU) | 1999-07-22 | — | — | WO | disclosed |