SCHEMBL6466868

SCHEMBL6466868

CC1(C)OC2CCCCC2O1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8141964 1.00 MAPK1 (0.39) MAPK1NPSR1L3MBTL1CYP3A4CYP2D6
SCHEMBL10689947 1.00 MAPK1 (0.39) MAPK1NPSR1L3MBTL1CYP3A4CYP2D6
SCHEMBL12633006 1.00 MAPK1 (0.39) MAPK1NPSR1L3MBTL1CYP3A4CYP2D6
SCHEMBL15483027 0.94 L3MBTL1 (0.35) MAPK1NPSR1L3MBTL1
SCHEMBL18840312 0.94 L3MBTL1 (0.35) MAPK1NPSR1L3MBTL1
SCHEMBL14790100 0.94 L3MBTL1 (0.35) MAPK1NPSR1L3MBTL1
SCHEMBL31741256 0.94 L3MBTL1 (0.35) MAPK1NPSR1L3MBTL1
SCHEMBL6123055 0.82 L3MBTL1 (0.31) L3MBTL1
SCHEMBL18840314 0.78 MAPK1 (0.34) MAPK1NPSR1L3MBTL1ALDH1A1
SCHEMBL1132322 0.78 MAPK1 (0.32) MAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11687000-B2 Sulfonium compound, chemically amplified resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-27 US disclosed
US-9989849-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-06-05 US disclosed
US-20170131634-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-05-11 US disclosed
EP-1758883-B1 Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors SCHERING CORP (US) 2011-11-02 EP disclosed
WO-2005116009-A1 SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS SCHERING CORPORATION (US) 2005-12-08 WO disclosed
US-20050058725-A1 Combination therapy including a matrix metalloproteinase inhibitor and an antineoplastic agent MCKEARN JOHN P (US) 2005-03-17 US disclosed
US-4761491-A Preparation of 2-substituted-1,3-dioxacycloalkanes from diols and diunsaturated ethers THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050058725-A1 Combination therapy including a matrix metalloproteinase inhibitor and an antineoplastic agent MMP3, MMP10, MMP25 MAPK1 3095/4885NPSR1 3589/4885L3MBTL1 1485/4885
US-11687000-B2 Sulfonium compound, chemically amplified resist composition, and patterning process ETV6, PKD1, PKD2 MAPK1 1296/4885NPSR1 3756/4885L3MBTL1 3765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.