Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463414 | 0.79 | CTSS (0.44) | NPC1RAB9AMMP1MMP2MMP3 | |
| SCHEMBL6468626 | 0.79 | CTSS (0.44) | NPC1RAB9AMMP1MMP2MMP3 | |
| SCHEMBL7048589 | 0.77 | CNR1 (0.48) | CNR1PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6062029 | 0.77 | CNR1 (0.48) | CNR1PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6463758 | 0.76 | CNR1 (0.51) | CNR1MAOBPRSS1PRSS2PRSS3 | |
| SCHEMBL6472179 | 0.74 | MMP3 (0.44) | MMP1MMP2MMP3 | |
| SCHEMBL6802148 | 0.74 | NPC1 (0.57) | CNR1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6473317 | 0.70 | MMP1 (0.40) | NPC1RAB9AMMP1MMP2MMP3 | |
| SCHEMBL13560007 | 0.69 | CNR1 (0.54) | CNR1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22834080 | 0.69 | CNR1 (0.46) | CNR1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |