Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463908 | 0.80 | ALDH1A1 (0.44) | NPY5RMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6468063 | 0.71 | MCHR1 (0.38) | MAPTMEN1KMT2AATM | |
| SCHEMBL6533656 | 0.67 | ALDH1A1 (0.47) | MAPTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL5563099 | 0.66 | ALDH1A1 (0.40) | MEN1KMT2AATM | |
| SCHEMBL9878124 | 0.60 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL23745244 | 0.59 | DDB1 (0.51) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2563428 | 0.59 | DDB1 (0.51) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11486845 | 0.58 | SMN1; SMN2 (0.85) | SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL28259164 | 0.57 | ALDH1A1 (0.45) | MAPTATM | |
| SCHEMBL19732959 | 0.56 | USP2 (0.56) | TP53SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | claimed |