Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046316 | 0.88 | CHRM5 (0.36) | LMNAPKMHDAC3HDAC4HDAC1 | |
| SCHEMBL6466391 | 0.83 | LMNA (0.35) | LMNAPKMSIGMAR1OPRM1OPRD1 | |
| SCHEMBL6475520 | 0.76 | DAGLA (0.50) | FAAH | |
| SCHEMBL6063277 | 0.74 | LMNA (0.37) | LMNAPKMSIGMAR1OPRM1OPRD1 | |
| SCHEMBL7567535 | 0.73 | DAGLA (0.43) | LMNAPKMFAAHKMT2A | |
| SCHEMBL7046896 | 0.73 | CCR6 (0.33) | LMNAPKMOPRM1OPRD1OPRK1 | |
| SCHEMBL7416860 | 0.71 | CHRM2 (0.33) | LMNAPKMOPRM1OPRD1OPRK1 | |
| SCHEMBL7416862 | 0.71 | CHRM2 (0.33) | LMNAPKMOPRM1OPRD1OPRK1 | |
| SCHEMBL6467733 | 0.71 | ALDH1A1 (0.36) | LMNAPKMCYP2C19HPGDALDH1A1 | |
| SCHEMBL6467199 | 0.70 | DAGLA (0.41) | LMNAPKMHPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |