Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567535 | 0.89 | DAGLA (0.43) | DAGLACES1LMNAPKMNAPEPLD | |
| SCHEMBL6461813 | 0.84 | P2RX7 (0.40) | DAGLAEPHX2 | |
| SCHEMBL7558531 | 0.82 | DAGLA (0.39) | DAGLALMNAPKMTBXA2RNPC1 | |
| SCHEMBL6467926 | 0.80 | DAGLA (0.44) | DAGLACES1LMNAPKMHPGD | |
| SCHEMBL7047979 | 0.78 | TBXA2R (0.41) | DAGLALMNATBXA2RHPGDSMN1; SMN2 | |
| SCHEMBL7044843 | 0.78 | L3MBTL1 (0.39) | DAGLALMNATBXA2RHPGDNPC1 | |
| SCHEMBL6461816 | 0.78 | DAGLA (0.42) | DAGLACES1NPC1RAB9AMAPK1 | |
| SCHEMBL7186571 | 0.77 | MASP2 (0.38) | DAGLALMNATBXA2RHPGDRAB9A | |
| SCHEMBL6475520 | 0.74 | DAGLA (0.50) | DAGLACES1 | |
| SCHEMBL7049295 | 0.72 | DAGLA (0.41) | DAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |