Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560844 | 0.87 | ADRA1D (0.36) | FBP1LMNAMAPTMAPK1RAB9A | |
| SCHEMBL4560843 | 0.87 | ADRA1D (0.36) | FBP1LMNAMAPTMAPK1RAB9A | |
| SCHEMBL6468215 | 0.83 | APOBEC3A (0.33) | GAAMAPT | |
| SCHEMBL12299771 | 0.73 | ADRA1D (0.35) | — | |
| SCHEMBL12966278 | 0.73 | APOBEC3A (0.46) | FBP1LMNAPOLBGAANPC1 | |
| SCHEMBL17516016 | 0.70 | CRHR1 (0.35) | LMNAGAAMAPT | |
| SCHEMBL16166528 | 0.70 | FBP1 (0.33) | FBP1LMNAMAPT | |
| SCHEMBL16166527 | 0.70 | FBP1 (0.33) | FBP1LMNAMAPT | |
| SCHEMBL16166360 | 0.69 | ADRA1D (0.35) | NPC1MAPTMAPK1RAB9A | |
| SCHEMBL4537574 | 0.69 | TEAD3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062229-A1 | A METHOD OF MANUFACTURING (-)-L-(3-HYDROXYPROPYL)-5-[(2R)-2-({2,2,2-TRIFLUOROETHOXY)- PHENOXYETHYL}AMINO)PROPYL]-2,3-DIHYDRO-LH-INDOLE-7-CARBOXAMIDE | ZENTIVA, K.S. (CZ) | 2012-05-18 | — | — | WO | disclosed |