Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18602960 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPK1AOC3TP53MAPT | |
| SCHEMBL19335729 | 0.80 | ALDH1A1 (0.37) | SIGMAR1ALDH1A1MAPK1TP53MAPT | |
| SCHEMBL28474702 | 0.80 | ALDH1A1 (0.37) | SIGMAR1ALDH1A1MAPK1TP53MAPT | |
| Bromide SCHEMBL28488926 | 0.78 | ALDH1A1 (0.36) | SIGMAR1ALDH1A1MAPK1TP53MAPT | |
| Hydrochloric Acid SCHEMBL10688474 | 0.75 | TP53 (0.33) | SIGMAR1ALDH1A1MAPK1TP53MAPT | |
| SCHEMBL25658373 | 0.75 | LMNA (0.38) | SMN1; SMN2DRD3HTR2AHRH1 | |
| SCHEMBL19148908 | 0.74 | MAOA (0.37) | SIGMAR1ALDH1A1MAPK1TP53SMN1; SMN2 | |
| SCHEMBL25896507 | 0.71 | SIGMAR1 (0.53) | SIGMAR1TP53TSHR | |
| SCHEMBL19149899 | 0.71 | MAOA (0.35) | SIGMAR1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4723633 | 0.71 | SIGMAR1 (0.31) | SIGMAR1TP53DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |