SCHEMBL6469138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6449845	0.82	TMPRSS4 (0.55)	GLAHPGDGAAKDM4EPOLB
	SCHEMBL18668519	0.77	ALDH1A1 (0.57)	GLAHPGDGAAKDM4EPOLB
	SCHEMBL17111063	0.75	ALDH1A1 (0.56)	GLAHPGDGAAKDM4EALDH1A1
	SCHEMBL18668549	0.74	ALDH1A1 (0.62)	GLAHPGDGAAPOLBALDH1A1
	SCHEMBL15929894	0.72	HTT (0.58)	GLAHPGDKDM4EALDH1A1MEN1
	SCHEMBL707320	0.72	ALDH1A1 (0.63)	GLAHPGDGAAKDM4EALDH1A1
	SCHEMBL7827542	0.72	GAA (0.77)	GLAHPGDGAAKDM4EPOLB
	SCHEMBL27515324	0.72	GLA (0.58)	GLAHPGDGAAKDM4EPOLB
	SCHEMBL19976665	0.72	GLA (0.52)	GLAHPGDGAAKDM4EPOLB
	SCHEMBL16761935	0.72	PTGS1 (0.58)	GLAHPGDGAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.