Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA7 | P43166 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470890 | 0.75 | HSP90AB1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9449619 | 0.74 | HSD17B1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1051805 | 0.73 | PTPN1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL935744 | 0.73 | MLYCD (0.41) | CA2ALDH1A1ESR1ESR2 | |
| SCHEMBL6907862 | 0.71 | ALDH1A1 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6900881 | 0.70 | AKR1B1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9123360 | 0.70 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9594874 | 0.70 | FSCN1 (0.58) | ALDH1A1TSHRHSD17B10CYP3A4MAPK1 | |
| SCHEMBL16520525 | 0.67 | ALDH1A1 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL472317 | 0.67 | ALDH1A1 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171194-A1 | Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions | YU RUEY J (US) | 2005-08-04 | — | — | US | claimed |
| WO-2005055947-A2 | ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS | YU RUEY J (US) | 2005-06-23 | — | — | WO | claimed |
| US-4182899-A | Optical resolution of amino acids into optical antipodes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | claimed |
| US-20050171194-A1 | Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions | YU RUEY J (US) | 2005-08-04 | — | — | US | disclosed |
| EP-0001319-A1 | Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained | BEECHAM GROUP PLC (GB) | 1979-04-04 | — | — | EP | disclosed |
| US-3994962-A | INTERMEDIATE FOR PENICILLIN AND CEPHALOSPORIN DERIVATIVES | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |