Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276952 | 0.77 | ADORA2A (0.46) | AHCYALDH1A1 | |
| SCHEMBL9149409 | 0.76 | ADORA2B (0.34) | — | |
| SCHEMBL3084463 | 0.69 | — | — | |
| SCHEMBL1232190 | 0.69 | — | — | |
| SCHEMBL9405168 | 0.68 | AHCY (0.33) | AHCY | |
| SCHEMBL8328715 | 0.67 | ADORA2A (0.33) | AHCYALDH1A1 | |
| SCHEMBL7680204 | 0.67 | AHCY (0.66) | AHCYALDH1A1 | |
| SCHEMBL5960487 | 0.64 | MEN1 (0.30) | — | |
| SCHEMBL9397384 | 0.63 | — | — | |
| SCHEMBL7420628 | 0.58 | FDPS (0.54) | AHCYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188011-B1 | Optimization of ligand affinity for RNA targets using mass spectrometry | ISIS PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20050142581-A1 | Microrna as ligands and target molecules | ISIS PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| US-6849660-B1 | Antimicrobial biaryl compounds | ISIS PHARMACEUTICALS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-6770486-B1 | IDENTIFICATION OF LIGAND COMPOUNDS THAT BIND TO TARGET MOLECULES SUCH AS PROTEINS OR STRUCTURED RNA WITH AS LITTLE AS MILLIMOLAR (MM) AFFINITY USING MASS SPECTROMETRY | ISIS PHARMACEUTICALS, INC. | 2004-08-03 | — | — | US | disclosed |