Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL6469728

[O-]B([O-])[O-].[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UQCRB P14927 1/20 0.38
ALDH1A1 P00352 2/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
MGLL Q99685 1/20 0.33
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NOTUM Q6P988 1/20 0.32
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL6471806 0.89 CA1 (0.41) UQCRBALDH1A1CA1CA2MGLL
SCHEMBL4177732 0.85 HIF1A (0.38) UQCRBCA1CA2MGLLHIF1A
Tetraphenylphosphonium SCHEMBL4428554 0.85 HIF1A (0.41) ALDH1A1MGLLHIF1ACYP1A2CYP3A4
Tetraphenylphosphonium SCHEMBL6567177 0.85 HIF1A (0.41) ALDH1A1MGLLHIF1ACYP1A2CYP3A4
Tetraphenylphosphonium SCHEMBL7172885 0.83 HIF1A (0.39) ALDH1A1MGLLHIF1ACYP1A2CYP3A4
Tetraphenylphosphonium SCHEMBL28123051 0.83 HIF1A (0.39) ALDH1A1CA1CA2MGLLHIF1A
Tetraphenylphosphonium SCHEMBL49763 0.83 HIF1A (0.39) ALDH1A1CA1CA2MGLLHIF1A
Tetraphenylphosphonium SCHEMBL7179570 0.78 HIF1A (0.36) HIF1ATAAR1TDP1
Tetraphenylphosphonium SCHEMBL27483478 0.75 CA4 (0.39) ALDH1A1CA1CA2MGLLHIF1A
Tetraphenylphosphonium SCHEMBL7132231 0.75 HIF1A (0.38) MGLLHIF1ACYP3A4HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448574-B1 PHOSPHORUS-BORATES WITH LOW MELTING POINTS MERCK PATENT GMBH (DE) 2005-06-15 EP claimed
US-20050000824-A1 Batteries, capacitors; electrolytic cells MERCK PATENTS GMBH (DE) 2005-01-06 US claimed
EP-1448574-B1 PHOSPHORUS-BORATES WITH LOW MELTING POINTS MERCK PATENT GMBH (DE) 2005-06-15 EP disclosed
US-20050000824-A1 Batteries, capacitors; electrolytic cells MERCK PATENTS GMBH (DE) 2005-01-06 US disclosed