Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL6471806

OB(O)O.[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.[O-]c1ccc(-c2ccc([O-])cc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
MGLL Q99685 3/20 0.41
CA2 P00918 2/20 0.41
UQCRB P14927 1/20 0.37
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36
ALDH1A1 P00352 2/20 0.33
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
ENPP2 Q13822 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL6469728 0.89 UQCRB (0.38) CA1MGLLCA2UQCRBMMP3
SCHEMBL4177732 0.84 HIF1A (0.38) CA1MGLLCA2UQCRBHIF1A
Tetraphenylphosphonium SCHEMBL49763 0.81 HIF1A (0.39) CA1MGLLCA2ALDH1A1HIF1A
Tetraphenylphosphonium SCHEMBL28123051 0.81 HIF1A (0.39) CA1MGLLCA2ALDH1A1HIF1A
Tetraphenylphosphonium SCHEMBL27483478 0.79 CA4 (0.39) CA1MGLLCA2ALDH1A1CA4
Tetraphenylphosphonium SCHEMBL7172888 0.79 CA4 (0.39) CA1MGLLCA2ALDH1A1CA4
Tetraphenylphosphonium SCHEMBL8468776 0.76 CA12 (0.50) CA1CA2MMP3BCL2L1ALDH1A1
Hydrochloric Acid SCHEMBL7930532 0.74 ALDH1A1 (0.50) CA1MGLLCA2MMP3BCL2L1
Tetraphenylphosphonium SCHEMBL7176299 0.74 HIF1A (0.38) CA1MGLLCA2ALDH1A1CA4
Bromide SCHEMBL7887989 0.74 ALDH1A1 (0.50) CA1MGLLCA2MMP3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448574-B1 PHOSPHORUS-BORATES WITH LOW MELTING POINTS MERCK PATENT GMBH (DE) 2005-06-15 EP claimed
US-20050000824-A1 Batteries, capacitors; electrolytic cells MERCK PATENTS GMBH (DE) 2005-01-06 US claimed
EP-1448574-B1 PHOSPHORUS-BORATES WITH LOW MELTING POINTS MERCK PATENT GMBH (DE) 2005-06-15 EP disclosed
US-20050000824-A1 Batteries, capacitors; electrolytic cells MERCK PATENTS GMBH (DE) 2005-01-06 US disclosed