Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15500843 | 0.79 | L3MBTL1 (0.48) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL11181964 | 0.76 | CASP3 (0.48) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL27606214 | 0.75 | ELANE (0.50) | POLBMAPTALDH1A1PLAUELANE | |
| SCHEMBL9375354 | 0.73 | L3MBTL1 (0.54) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL9815841 | 0.72 | L3MBTL1 (0.57) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL984297 | 0.72 | L3MBTL1 (0.57) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL6003824 | 0.72 | MGLL (0.43) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL6002581 | 0.72 | MGLL (0.41) | CASP3SENP8SENP7SENP6POLB | |
| SCHEMBL6002576 | 0.72 | RAB9A (0.49) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6004192 | 0.72 | KMT2A (0.58) | CASP3SENP8SENP7SENP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603897-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080999-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2004-09-23 | — | — | WO | disclosed |