Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470096 | 1.00 | MMP9 (0.46) | MMP9CXCL12CXCR4TSHRMAPK1 | |
| SCHEMBL6470091 | 1.00 | MMP9 (0.46) | MMP9CXCL12CXCR4TSHRMAPK1 | |
| SCHEMBL6469881 | 0.82 | MEN1 (0.50) | TSHRMAPK1TAAR1MEN1ALDH1A1 | |
| SCHEMBL6470101 | 0.76 | TAAR1 (0.48) | TSHRMAPK1TAAR1 | |
| SCHEMBL6470337 | 0.75 | TSHR (0.47) | TSHRMAPK1TAAR1 | |
| SCHEMBL2951837 | 0.72 | NFE2L2 (0.73) | CXCL12CXCR4 | |
| SCHEMBL5317115 | 0.72 | NFE2L2 (0.73) | CXCL12CXCR4 | |
| SCHEMBL6470975 | 0.70 | TAAR1 (0.43) | TSHRMAPK1TAAR1MEN1ALDH1A1 | |
| SCHEMBL27758491 | 0.69 | CALM1 (0.66) | TSHRMAPK1TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL13131818 | 0.69 | TAAR1 (0.61) | TSHRMAPK1TAAR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050031717-A1 | Using capsaicin receptors; complexing | VIRGINIA COMMONWEALTH UNIVERSITY | 2005-02-10 | — | — | US | disclosed |
| WO-2005006881-A2 | SALT TASTE MODIFICATION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |