Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252686 | 0.95 | MMP13 (0.53) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6533924 | 0.93 | MMP13 (0.49) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6730796 | 0.93 | MMP13 (0.49) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6258183 | 0.92 | MMP13 (0.48) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6730265 | 0.92 | MMP13 (0.48) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6476942 | 0.92 | MMP13 (0.48) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6724753 | 0.92 | MMP13 (0.48) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6470824 | 0.91 | MMP13 (0.50) | TRPA1MMP13MEN1KMT2ALMNA | |
| SCHEMBL6258115 | 0.91 | TRPA1 (0.49) | TRPA1MMP13LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6730594 | 0.91 | MMP13 (0.48) | TRPA1MMP13MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370562-A1 | THIENO[2,3-D]PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-17 | — | — | EP | claimed |
| EP-0927273-B1 | PHENOLIC STAIN-RESISTS | DU PONT (US) | 2003-03-12 | — | — | EP | claimed |
| US-20030004172-A1 | Fused pyrimidinone matrix metalloproteinase inhibitors | HARTER WILLIAM GLEN (US) | 2003-01-02 | — | — | US | claimed |
| WO-2002064598-A1 | THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |
| EP-0891413-A1 | PREVENTION OF DYE-BLEEDING AND TRANSFER DURING LAUNDERING | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-20 | — | — | EP | claimed |
| US-5725889-A | TO ACID DYES, POLYAMIDE FIBERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-10 | — | — | US | claimed |
| US-5707949-A | DETERGENT ADDITIVE, RESOLE FROM BIS(HYDROXYPHENYL)SULFONE AND FORMALDEHYDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-13 | — | — | US | claimed |
| EP-0682726-B1 | BIS(HYDROXYPHENYL)SULFONE RESOLES AS POLYAMIDE STAIN-RESISTS | DU PONT (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1997038077-A1 | PREVENTION OF DYE-BLEEDING AND TRANSFER DURING LAUNDERING | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-16 | — | — | WO | claimed |
| EP-0682726-A1 | BIS(HYDROXYPHENYL)SULFONE RESOLES AS POLYAMIDE STAIN-RESISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-22 | — | — | EP | claimed |
| US-5460891-A | Resoles from fromaldehyde and bis(hydroxyphenyl) sulfone | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-10-24 | — | — | US | claimed |
| US-5447755-A | Applying to polyamide substrates, base catalyzed resole of of sulfone with formaldehyde | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-09-05 | — | — | US | claimed |
| WO-1994018378-A1 | BIS(HYDROXYPHENYL)SULFONE RESOLES AS POLYAMIDE STAIN-RESISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-18 | — | — | WO | claimed |
| EP-1585749-A1 | DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS | PFIZER INC. (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1530475-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING AN ALLOSTERIC CARBOXYLIC INHIBITOR OF MATRIX METALLOPROTEINASE-13 AND A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 | Warner-Lambert Company LLC (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004063198-A1 | DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS | PFIZER INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-0682726-A1 | BIS(HYDROXYPHENYL)SULFONE RESOLES AS POLYAMIDE STAIN-RESISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5460891-A | Resoles from fromaldehyde and bis(hydroxyphenyl) sulfone | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5447755-A | Applying to polyamide substrates, base catalyzed resole of of sulfone with formaldehyde | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-09-05 | — | — | US | disclosed |
| WO-1994018378-A1 | BIS(HYDROXYPHENYL)SULFONE RESOLES AS POLYAMIDE STAIN-RESISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004172-A1 | Fused pyrimidinone matrix metalloproteinase inhibitors | MMP13, MMP3, MMP25 | TRPA1 3888/4885MMP13 1/4885MEN1 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.