Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL28521237 | 0.92 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRNR4A2ABL1 | |
| SCHEMBL2895994 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRABL1LMNA | |
| SCHEMBL28234218 | 0.83 | TSHR (0.42) | ALDH1A1LMNATSHRGAAMAPT | |
| SCHEMBL27475798 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRABL1LMNA | |
| SCHEMBL993113 | 0.81 | TSHR (0.59) | ALDH1A1HSD17B10CFTRNR4A2LMNA | |
| SCHEMBL31589985 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRABL1LMNA | |
| SCHEMBL505249 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRABL1LMNA | |
| SCHEMBL15771342 | 0.81 | NPC1 (0.49) | ALDH1A1LMNAMAPTKMT2ACA1 | |
| SCHEMBL110117 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10LMNATSHRGAA | |
| SCHEMBL15771897 | 0.81 | GRM6 (0.40) | ALDH1A1HSD17B10CFTRLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184526-A | Preparation method of 2-amino-3-chlorobenzoic acid methyl ester | 鹤壁市宝瑞德化工有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115997767-A | Herbicide for weed control plant protection and time precise control method | 贵州省生物技术研究所(贵州省生物技术重点实验室、贵州省马铃薯研究所、贵州省食品加工研究所) | 2023-04-25 | — | — | CN | claimed |
| WO-2022116451-A1 | CASSAVA FIELD POST-EMERGENCE HERBICIDE TAKING EFFICIENT HALOXYFOP-METHYL AS EFFECTIVE COMPONENT | 海南大学 | 2022-06-09 | — | — | WO | claimed |
| CN-112400883-A | Cassava field post-emergence herbicide with efficient haloxyfop-methyl as effective component | 海南大学 | 2021-02-26 | — | — | CN | claimed |
| CN-108047069-A | A kind of preparation method of 2- amino -3- chloro benzoic ethers | 南通泰禾化工股份有限公司 | 2018-05-18 | — | — | CN | claimed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| EP-4467199-A2 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2024-11-27 | — | — | EP | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024222814-A1 | CYP11B2 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-10-31 | — | — | WO | disclosed |
| EP-3976597-B1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-28 | — | — | EP | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| US-20240199605-A1 | SMALL MOLECULAR INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-20 | — | — | US | disclosed |
| EP-0330137-A1 | Intermediate compounds for the preparation of 1,2,4-triazolo [1,5-a]pyrimidine-2-sulfonamides | DowElanco (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4818273-A | Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides | THE DOW CHEMICAL COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4306074-A | Preparation of a mixture of an alkyl 3-chloroanthranilate and an alkyl 6-chloroanthranilate | BASF AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| EP-0020969-A1 | Process for the preparation of a mixture of 3-chloro-anthranilic acid alkyl ester and 6-chloro-anthranilic acid alkyl ester | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | IRAK3, IKBKB, IKBKG | ALDH1A1 3824/4885HSD17B10 1345/4885CFTR 668/4885 |
| US-20240199605-A1 | SMALL MOLECULAR INHIBITORS OF NF-kB INDUCING KINASE | NFKBIA, IKBKB, IKBKE | ALDH1A1 4012/4885HSD17B10 1321/4885CFTR 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.