Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895994 | 0.90 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL28957307 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL31634613 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL14828745 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL465737 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL647085 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL505249 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL31589985 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CFTRTSHRLMNA | |
| SCHEMBL27508673 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRLMNACA1 | |
| SCHEMBL305237 | 0.80 | TSHR (0.61) | ALDH1A1HSD17B10CFTRTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168720-C | Aryl alkanoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1305465-A | Aryl alkanoylpyridazines | MERCK PATENT GMBH (DE) | 2001-07-25 | — | — | CN | disclosed |