Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472021 | 0.81 | LMNA (0.40) | SMN1; SMN2CNR2KRASKDM4ECNR1 | |
| SCHEMBL1408375 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2GPR3KDM4EMAPTALDH1A1 | |
| SCHEMBL18566674 | 0.76 | GPR3 (0.58) | GPR3KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL3049158 | 0.69 | L3MBTL1 (0.61) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL31384383 | 0.69 | L3MBTL1 (0.61) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL29446458 | 0.69 | L3MBTL1 (0.61) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL15073552 | 0.69 | KDM4E (0.50) | SMN1; SMN2KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL10277286 | 0.69 | POLB (0.65) | CNR2KRASKDM4EMAPTCNR1 | |
| SCHEMBL19163665 | 0.68 | PDE7A (0.42) | SMN1; SMN2CNR2KDM4EMAPTALDH1A1 | |
| SCHEMBL22721384 | 0.68 | L3MBTL1 (0.44) | SMN1; SMN2CNR2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554262-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Glenmark Pharmaceuticals Limited (IN) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037805-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-05-06 | — | — | WO | disclosed |