Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539939 | 0.87 | MAOA (0.49) | ALDH1A1MAPK1MAOAMAOBKDM4E | |
| SCHEMBL17346308 | 0.75 | FDPS (0.54) | ALDH1A1MAPK1KDM4EATMFDPS | |
| SCHEMBL1539938 | 0.75 | MAOA (0.41) | ALDH1A1MAPK1MAOAMAOBKDM4E | |
| SCHEMBL17345977 | 0.73 | FDPS (0.56) | ALDH1A1MAPK1KDM4EATMFDPS | |
| SCHEMBL17335852 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAOAMAOBKMT2A | |
| SCHEMBL7306003 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBSLC6A4 | |
| SCHEMBL5683208 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAOAMAOBCYP1A2 | |
| SCHEMBL17346304 | 0.71 | DRD2 (0.50) | ALDH1A1MAPK1KDM4EFDPSKMT2A | |
| SCHEMBL1541274 | 0.70 | MAOA (0.55) | ALDH1A1MAPK1MAOAMAOBSLC6A4 | |
| SCHEMBL385308 | 0.70 | MAOA (0.55) | ALDH1A1MAPK1MAOAMAOBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |