Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470905 | 0.91 | CXCR3 (0.49) | TSHRLMNAMAPK1ALDH1A1CXCR3 | |
| SCHEMBL6470927 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TRPM8 | |
| SCHEMBL6472270 | 0.77 | MEN1 (0.56) | TRPM8 | |
| SCHEMBL9633041 | 0.77 | RAB9A (0.60) | TSHRLMNAMAPK1ALDH1A1NPC1 | |
| SCHEMBL6472196 | 0.75 | DUSP3 (0.48) | TSHRLMNAMAPK1 | |
| SCHEMBL8816740 | 0.75 | TSHR (0.56) | TSHRLMNAMAPK1ALDH1A1NPC1 | |
| SCHEMBL9631943 | 0.75 | RAB9A (0.60) | TSHRLMNAMAPK1ALDH1A1NPC1 | |
| SCHEMBL30960133 | 0.73 | TSHR (0.75) | TSHRMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL29227699 | 0.73 | TSHR (0.75) | TSHRMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL6471647 | 0.73 | MEN1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050031717-A1 | Using capsaicin receptors; complexing | VIRGINIA COMMONWEALTH UNIVERSITY | 2005-02-10 | — | — | US | disclosed |
| WO-2005006881-A2 | SALT TASTE MODIFICATION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |