Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156289 | 1.00 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14363017 | 0.86 | CA1 (0.46) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1276291 | 0.84 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1276292 | 0.84 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11553504 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28260564 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL647313 | 0.81 | FTO (0.59) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL647314 | 0.81 | FTO (0.59) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL10156264 | 0.78 | ALDH1A1 (0.57) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10156271 | 0.78 | ALDH1A1 (0.57) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119778-B2 | Reversibly thermochromic compositions | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2032370-B1 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | BASF SE (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100234494-A1 | Reversibly thermochromic compositions | CIBA CORPORATION | 2010-09-16 | — | — | US | disclosed |
| EP-2032370-A2 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | Ciba Holding Inc. (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147843-A2 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | CIBA HOLDING INC. (CH) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234494-A1 | Reversibly thermochromic compositions | CRY1, REL, CRY2 | MAPT 59/4885MEN1 937/4885KMT2A 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.