Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199701 | 0.80 | DRD2 (0.39) | MMEDRD2DRD3OPRM1OPRD1 | |
| SCHEMBL21753640 | 0.79 | TSHR (0.35) | OPRK1TAAR1 | |
| SCHEMBL5710769 | 0.79 | TSHR (0.35) | OPRK1TAAR1 | |
| SCHEMBL7571358 | 0.77 | TAAR1 (0.44) | MMEDRD2DRD3OPRM1OPRD1 | |
| SCHEMBL2729032 | 0.74 | SLC6A2 (0.48) | OPRK1TAAR1MEN1KMT2A | |
| SCHEMBL21056125 | 0.74 | SLC6A2 (0.48) | OPRK1TAAR1MEN1KMT2A | |
| SCHEMBL27515553 | 0.74 | SLC6A2 (0.48) | OPRK1TAAR1MEN1KMT2A | |
| SCHEMBL680803 | 0.73 | — | — | |
| SCHEMBL23121590 | 0.73 | PNMT (0.43) | OPRK1TAAR1 | |
| SCHEMBL635206 | 0.73 | PNMT (0.43) | OPRK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |