Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473187 | 0.89 | MAPT (0.54) | PKMKMT2AHTR6ALDH1A1MAPT | |
| SCHEMBL4486179 | 0.89 | HTR6 (0.55) | PKMKMT2AHTR6ALDH1A1MAPT | |
| SCHEMBL6476587 | 0.86 | MAPT (0.54) | PKMKMT2AHTR6PGRALDH1A1 | |
| SCHEMBL6475761 | 0.83 | ESR1 (0.46) | PKMKMT2AHTR6KDM4EALDH1A1 | |
| SCHEMBL16551093 | 0.79 | HTR6 (0.64) | PKMHTR6PGR | |
| SCHEMBL6475723 | 0.74 | HTR6 (0.80) | PKMHTR6PGRKDM4EALDH1A1 | |
| SCHEMBL16551615 | 0.71 | HTR6 (0.61) | PKMKMT2AHTR6ALDH1A1MEN1 | |
| SCHEMBL13865317 | 0.70 | GAA (0.41) | KMT2AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5781207 | 0.69 | HTR6 (0.74) | PKMHTR6PGRMAPTLMNA | |
| SCHEMBL16551297 | 0.69 | HTR6 (0.53) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037830-A1 | PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2005037830-A1 | PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2005-04-28 | — | — | WO | disclosed |