Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.80 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 8/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482936 | 0.89 | HTR6 (0.81) | HTR6PKMCCNT1CDK9LMNA | |
| SCHEMBL4480862 | 0.89 | HTR6 (1.00) | HTR6DDB1CRBNPKMCCNT1 | |
| SCHEMBL4477508 | 0.89 | HTR6 (0.80) | HTR6KDRAURKBPGRPKM | |
| Water SCHEMBL4559433 | 0.88 | HTR6 (0.98) | HTR6DDB1CRBNPKMCCNT1 | |
| Water SCHEMBL4559431 | 0.88 | HTR6 (0.98) | HTR6DDB1CRBNPKMCCNT1 | |
| SCHEMBL6472087 | 0.86 | HTR6 (0.76) | HTR6PGRLMNAMAPT | |
| SCHEMBL6476010 | 0.83 | HTR6 (0.81) | HTR6CCNT1CDK9KDM4ELMNA | |
| SCHEMBL3324653 | 0.80 | HTR6 (0.72) | HTR6PGRALDH1A1BRD4 | |
| SCHEMBL6472057 | 0.74 | PKM (0.45) | HTR6KDRAURKBPGRPKM | |
| SCHEMBL5781207 | 0.71 | HTR6 (0.74) | HTR6PGRPKMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037830-A1 | PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2005-04-28 | — | — | WO | claimed |