SCHEMBL6472955

SCHEMBL6472955

c1ccc(-c2cc(-c3cccc4ccccc34)c(-c3cccc4ccccc34)c(-c3cccc4ccccc34)c2-c2cccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
MPI P34949 1/20 0.46
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
MAPK1 P28482 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TNF P01375 1/20 0.43
CA12 O43570 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140937 0.89 ALDH1A1 (0.40) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL30332655 0.85 MAPT (0.46) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL28954994 0.83 ALDH1A1 (0.40) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL9481417 0.82 MAPT (0.47) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL28594179 0.81 MAPT (0.44) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL4010018 0.81 KDM4E (0.44) KDM4EMEN1KMT2AALDH1A1MAPT
Biphenyl SCHEMBL4007752 0.81 MAPT (0.46) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL31122707 0.80 GPR84 (0.40) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL17442110 0.80 MEN1 (0.49) KDM4EMEN1KMT2AALDH1A1MAPT
SCHEMBL30022214 0.80 MEN1 (0.49) KDM4EMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6896723-B2 Compressed fluid formulation containing hole transporting material EASTMAN KODAK COMPANY (US) 2005-05-24 US disclosed
US-20040110866-A1 Compressed fluid formulation containing hole transporting material EASTMAN KODAK COMPANY 2004-06-10 US disclosed
EP-1427033-A2 A compressed fluid formulation containing electron transporting, hole injecting material, hole transporting material and electroluminescent material EASTMAN KODAK COMPANY (US) 2004-06-09 EP disclosed