Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6455838 | 0.98 | NPC1 (0.58) | NPC1RAB9APTPN1BLMKDM4E | |
| Acetic Acid SCHEMBL9057647 | 0.91 | HSD17B3 (0.53) | NPC1RAB9APTPN1BLMKDM4E | |
| Hydrochloric Acid SCHEMBL13738814 | 0.87 | GSK3B (0.42) | NPC1RAB9APTPN1BLMKDM4E | |
| SCHEMBL883159 | 0.82 | SMN1; SMN2 (0.50) | RAB9APTPN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8994647 | 0.81 | NPC1 (0.68) | NPC1RAB9APTPN1BLMKDM4E | |
| Hydrochloric Acid SCHEMBL690938 | 0.80 | SMN1; SMN2 (0.48) | RAB9APTPN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22919688 | 0.80 | PARP10 (0.50) | BLMALDH1A1POLBRECQLTDP1 | |
| SCHEMBL7824015 | 0.80 | TSHR (0.60) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL3181886 | 0.80 | LMNA (0.47) | NPC1RAB9AKDM4EPOLBAPEX1 | |
| SCHEMBL7939950 | 0.79 | NPC1 (0.81) | NPC1RAB9APTPN1BLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111443154-B | Research method of medicinal genetic relationship of glycyrrhiza | 贵州中医药大学 | 2023-03-07 | — | — | CN | claimed |
| CN-111443154-A | Research method of medicinal genetic relationship of glycyrrhiza | 贵州中医药大学 | 2020-07-24 | — | — | CN | claimed |
| CN-111333685-A | Synthetic method of FXR antagonist SIPI7623 metabolite | 江苏柯菲平医药股份有限公司 | 2020-06-26 | — | — | CN | claimed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | claimed |
| JP-3200751-A | — | — | None | — | — | JP | disclosed |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | SANOFI (FR) | 2024-04-18 | — | — | US | disclosed |
| US-20230382924-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
| US-20230382924-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
| CN-111443154-B | Research method of medicinal genetic relationship of glycyrrhiza | 贵州中医药大学 | 2023-03-07 | — | — | CN | disclosed |
| WO-2022076621-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |
| CN-113567639-A | Comprehensive evaluation method for quality of traditional Chinese medicinal materials | 中国食品药品检定研究院 | 2021-10-29 | — | — | CN | disclosed |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | NORTHEASTERN UNIVERSITY (US) | 2021-09-28 | — | — | US | disclosed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |
| JP-H03200751-A | PRODUCTION OF 2-AMINO-1-(4-HYDROXYPHENYL)-ETHANONE MINERAL ACID SALT | FUKUI KAGAKU KOGYO KK | 1991-09-02 | — | — | JP | disclosed |
| US-4533550-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1985-08-06 | — | — | US | disclosed |
| EP-0006712-B1 | HETEROCYCLIC DERIVATIVES OF (4-ARYLOXYMETHYL-1.3-DIOXOLAN-2-YL) METHYL-1H-IMIDAZOLES AND -1H-1.2.4-TRIAZOLES, THEIR PREPARATION AND THE DERIVATIVES FOR USE AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-11-30 | — | — | EP | disclosed |
| EP-0053539-A1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
| US-4313953-A | BACTERICIDES, FUNGICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-02-02 | — | — | US | disclosed |
| US-4218458-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-08-19 | — | — | US | disclosed |
| US-3987047-A | ANORETICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | GLUL, QPCT, DNPEP | NPC1 4848/4885RAB9A 1494/4885PTPN1 4635/4885 |
| US-20240124408-A1 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | TRPM8, TAS2R8, TRPM7 | NPC1 881/4885RAB9A 849/4885PTPN1 4795/4885 |
| US-20230382924-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | NPC1 154/4885RAB9A 1615/4885PTPN1 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.