Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042160 | 0.91 | BMP1 (0.40) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6465253 | 0.79 | BMP1 (0.38) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6473243 | 0.79 | BMP1 (0.41) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL7047599 | 0.75 | CASR (0.41) | ALDH1A1KMT2AMEN1TDP1HPGD | |
| SCHEMBL6462775 | 0.72 | CES1 (0.47) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6061916 | 0.71 | DAGLA (0.42) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL7042158 | 0.71 | DAGLA (0.42) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6463614 | 0.71 | HDAC1 (0.45) | ALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL10144081 | 0.68 | MAPT (0.57) | BMP1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6428437 | 0.67 | BMP1 (0.61) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |