Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047599 | 0.92 | CASR (0.41) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL6465251 | 0.81 | LMNA (0.40) | BMP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6473247 | 0.79 | BMP1 (0.42) | BMP1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6464300 | 0.76 | CTSS (0.44) | BMP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL7042160 | 0.75 | BMP1 (0.40) | BMP1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7047598 | 0.74 | CTSL (0.40) | KMT2ALMNAPOLBTP53 | |
| SCHEMBL6473321 | 0.70 | MEN1 (0.40) | BMP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6463649 | 0.70 | MEN1 (0.40) | BMP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6466336 | 0.69 | MEN1 (0.40) | BMP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL7043331 | 0.68 | CMA1 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |