Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042158 | 0.91 | DAGLA (0.42) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6462673 | 0.83 | MEN1 (0.42) | KMT2AMEN1RAB9AALDH1A1EPHX2 | |
| SCHEMBL6473321 | 0.82 | MEN1 (0.40) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6463649 | 0.82 | MEN1 (0.40) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6466336 | 0.81 | MEN1 (0.40) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6462775 | 0.81 | CES1 (0.47) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6465251 | 0.79 | LMNA (0.40) | BMP1KMT2AMEN1RAB9ACTSL | |
| SCHEMBL7047954 | 0.79 | F11 (0.47) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6061916 | 0.79 | DAGLA (0.42) | BMP1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6473247 | 0.79 | BMP1 (0.42) | BMP1KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |