SCHEMBL6473480

SCHEMBL6473480

COc1ccc(C(O)C(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 3/20 0.49
ESR2 Q92731 2/20 0.49
RAB9A P51151 2/20 0.49
CYP3A4 P08684 1/20 0.49
PPARG P37231 1/20 0.49
P4HB P07237 1/20 0.49
CALM1 P0DP23 1/20 0.49
F3 P13726 1/20 0.49
XDH P47989 1/20 0.49
CYP1A2 P05177 1/20 0.49
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
LTA4H P09960 1/20 0.48
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
NPC1 O15118 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68736 0.93 CES2 (0.55) MAPTMEN1KMT2AALDH1A1RAB9A
Methoxymethane SCHEMBL36596 0.91 CES2 (0.53) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL12168990 0.87 NPSR1 (0.56) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL8149482 0.86 CES2 (0.60) MAPTALDH1A1ESR2CYP3A4CYP1A2
SCHEMBL1927479 0.85 RAB9A (0.48) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL4809737 0.85 RAB9A (0.62) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL5444947 0.85 HPGD (0.62) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL9128631 0.85 CA1 (0.49) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29262742 0.85 LMNA (0.67) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL812736 0.85 LMNA (0.67) MAPTMEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005054169-A1 PREPARATION METHOD OF 2-PHENYLACETOPHENONE DERIVATIVES HANBUL COSMETIC CO., LTD. (KR) 2005-06-16 WO claimed
CN-1326358-A Method of DNA vaccination GLAXO GROUP LTD (GB) 2001-12-12 CN claimed
WO-2005054169-A1 PREPARATION METHOD OF 2-PHENYLACETOPHENONE DERIVATIVES HANBUL COSMETIC CO., LTD. (KR) 2005-06-16 WO disclosed
CN-1326358-A Method of DNA vaccination GLAXO GROUP LTD (GB) 2001-12-12 CN disclosed